86 research outputs found

    Wave speeds and Green’s tensors for shear wave propagation in incompressible, hyperelastic materials with uniaxial stretch

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    Assessing elastic material properties from shear wave propagation following an acoustic radiation force impulse (ARFI) excitation is difficult in anisotropic materials because of the complex relations among the propagation direction, shear wave polarizations, and material symmetries. In this paper, we describe a method to calculate shear wave signals using Green's tensor methods in an incompressible, hyperelastic material with uniaxial stretch. Phase and group velocities are determined for SH and SV propagation modes as a function of stretch by constructing the equation of motion from the Cauchy stress tensor determined from the strain energy density. The Green's tensor is expressed as the sum of contributions from the SH and SV propagation modes with the SH contribution determined using a closed-form expression and the SV contribution determined by numerical integration. Results are presented for a Mooney-Rivlin material model with a tall Gaussian excitation similar to an ARFI excitation. For an experimental configuration with a tilted material symmetry axis, results show that shear wave signals exhibit complex structures such as shear splitting that are characteristic of both the SH and SV propagation modes

    Quantum Concentration Inequalities

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    We establish Transportation Cost Inequalities (TCIs) with respect to the quantum Wasserstein distance by introducing quantum extensions of well-known classical methods: First, we generalize the Dobrushin uniqueness condition to prove that Gibbs states of 1D commuting Hamiltonians satisfy a TCI at any positive temperature and provide conditions under which this first result can be extended to non-commuting Hamiltonians. Next, using a non-commutative version of Ollivier’s coarse Ricci curvature, we prove that high temperature Gibbs states of commuting Hamiltonians on arbitrary hypergraphs H= (V, E) satisfy a TCI with constant scaling as O(|V|). Third, we argue that the temperature range for which the TCI holds can be enlarged by relating it to recently established modified logarithmic Sobolev inequalities. Fourth, we prove that the inequality still holds for fixed points of arbitrary reversible local quantum Markov semigroups on regular lattices, albeit with slightly worsened constants, under a seemingly weaker condition of local indistinguishability of the fixed points. Finally, we use our framework to prove Gaussian concentration bounds for the distribution of eigenvalues of quasi-local observables and argue the usefulness of the TCI in proving the equivalence of the canonical and microcanonical ensembles and an exponential improvement over the weak Eigenstate Thermalization Hypothesis

    Surveyor surface sampler instrument

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    Operational capabilities, methods of deployment command and control, areas of lunar operation, and television viewability of Surveyor lunar surface sampler instrumen

    Measuring elastic nonlinearity in a soft solid using a tilted acoustic radiation force for shear wave excitation

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    Excitation of multiple wave modes using shear wave elastography can result in additional information about the tissue's material characteristics and, potentially, improve disease diagnosis. Theoretically, tilting the acoustic radiation force excitation axis with respect to the material's symmetry axis should excite several wave modes in the material. In this work, we have experimentally demonstrated proof of concept in a uniaxially stretched phantom, while increasing the stretch level. Tilted acoustic radiation force experiments showed a clearly visible second wave mode across the stretch direction for larger stretches (>160%)

    Two spectroscopically confirmed galaxy structures at z=0.61 and 0.74 in the CFHTLS Deep~3 field

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    Adami et al. (2010) have detected several cluster candidates at z>0.5 as part of a systematic search for clusters in the Canada France Hawaii Telescope Legacy Survey, based on photometric redshifts. We focus here on two of them, located in the D3 field: D3-6 and D3-43. We have obtained spectroscopy with Gemini/GMOS and measured redshifts for 23 and 14 galaxies in the two structures. These redshifts were combined with those available in the literature. A dynamical and a weak lensing analysis were also performed, together with the study of X-ray Chandra archive data. Cluster D3-6 is found to be a single structure of 8 spectroscopically confirmed members at an average redshift z=0.607, with a velocity dispersion of 423 km/s. It appears to be a relatively low mass cluster. D3-43-S3 has 46 spectroscopically confirmed members at an average redshift z=0.739. It can be decomposed into two main substructures, having a velocity dispersion of about 600 and 350 km/s. An explanation to the fact that D3-43-S3 is detected through weak lensing (only marginally, at the ~3sigma level) but not in X-rays could be that the two substructures are just beginning to merge more or less along the line of sight. We also show that D3-6 and D3-43-S3 have similar global galaxy luminosity functions, stellar mass functions, and star formation rate (SFR) distributions. The only differences are that D3-6 exhibits a lack of faint early type galaxies, a deficit of extremely high stellar mass galaxies compared to D3-43-S3, and an excess of very high SFR galaxies. This study shows the power of techniques based on photometric redshifts to detect low to moderately massive structures, even at z~0.75.Comment: Accepted in A&A, final version, shortened abstrac

    guide to clinicians

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    Funding This work received an unrestricted grant from GSK Portugal and was supported by Sociedade Portuguesa de Ginecologia (SPG).Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered as indicators of either infection or dysregulated host response or response to treatment and/or aid clinicians to prognosticate patient risk. More than 250 biomarkers have been identified and evaluated over the last few decades, but no biomarker accurately differentiates between sepsis and sepsis-like syndrome. Published data support the use of biomarkers for pathogen identification, clinical diagnosis, and optimization of antibiotic treatment. In this narrative review, we highlight how clinicians could improve the use of pathogen-specific and of the most used host-response biomarkers, procalcitonin and C-reactive protein, to improve the clinical care of patients with sepsis. Biomarker kinetics are more useful than single values in predicting sepsis, when making the diagnosis and assessing the response to antibiotic therapy. Finally, integrated biomarker-guided algorithms may hold promise to improve both the diagnosis and prognosis of sepsis. Herein, we provide current data on the clinical utility of pathogen-specific and host-response biomarkers, offer guidance on how to optimize their use, and propose the needs for future research.publishersversionepub_ahead_of_prin

    ISOL@: an Italian SOLAnaceae genomics resource

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    BACKGROUND: Present-day '-omics' technologies produce overwhelming amounts of data which include genome sequences, information on gene expression (transcripts and proteins) and on cell metabolic status. These data represent multiple aspects of a biological system and need to be investigated as a whole to shed light on the mechanisms which underpin the system functionality.The gathering and convergence of data generated by high-throughput technologies, the effective integration of different data-sources and the analysis of the information content based on comparative approaches are key methods for meaningful biological interpretations.In the frame of the International Solanaceae Genome Project, we propose here ISOLA, an Italian SOLAnaceae genomics resource. RESULTS: ISOLA (available at http://biosrv.cab.unina.it/isola) represents a trial platform and it is conceived as a multi-level computational environment.ISOLA currently consists of two main levels: the genome and the expression level. The cornerstone of the genome level is represented by the Solanum lycopersicum genome draft sequences generated by the International Tomato Genome Sequencing Consortium. Instead, the basic element of the expression level is the transcriptome information from different Solanaceae species, mainly in the form of species-specific comprehensive collections of Expressed Sequence Tags (ESTs).The cross-talk between the genome and the expression levels is based on data source sharing and on tools that enhance data quality, that extract information content from the levels' under parts and produce value-added biological knowledge. CONCLUSIONS: ISOLA is the result of a bioinformatics effort that addresses the challenges of the post-genomics era. It is designed to exploit '-omics' data based on effective integration to acquire biological knowledge and to approach a systems biology view. Beyond providing experimental biologists with a preliminary annotation of the tomato genome, this effort aims to produce a trial computational environment where different aspects and details are maintained as they are relevant for the analysis of the organization, the functionality and the evolution of the Solanaceae family

    Phase and group velocities for shear wave propagation in an incompressible, hyperelastic material with uniaxial stretch

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    Abstract Objective. Determining elastic properties of materials from observations of shear wave propagation is difficult in anisotropic materials because of the complex relations among the propagation direction, shear wave polarizations, and material symmetries. In this study, we derive expressions for the phase velocities of the SH and SV propagation modes as a function of propagation direction in an incompressible, hyperelastic material with uniaxial stretch. Approach. Wave motion is included in the material model by adding incremental, small amplitude motion to the initial, finite deformation. Equations of motion for the SH and SV propagation modes are constructed using the Cauchy stress tensor derived from the strain energy function of the material. Group velocities for the SH and SV propagation modes are derived from the angle-dependent phase velocities. Main results. Sample results are presented for the Arruda–Boyce, Mooney–Rivlin, and Isihara material models using model parameters previously determined in a phantom. Significance. Results for the Mooney–Rivlin and Isihara models demonstrate shear splitting in which the SH and SV propagation modes have unequal group velocities for propagation across the material symmetry axis. In addition, for sufficiently large stretch, the Arruda–Boyce and Isihara material models show cusp structures with triple-valued group velocities for the SV mode at angles of roughly 15° to the material symmetry axis.</jats:p
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